Periosteal Osteosarcoma

A Periosteal Osteosarcoma is a cancerous bone tumor. It comes from within the bone (intramedullary). It is a cancerous tumor, and can lead to bone destruction. It is a slow growing tumor that will not spread to other parts of the body in most cases.

24C) Sag MR T2 Periosteal Osteosarcoma
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What is a Periosteal Osteosarcoma?

Periosteal Osteosarcoma is a cancerous bone tumor that produces bone. This is the most common type of bone tumor. This type of tumor occurs primarily in the bone of the femur, and humerus.

Who is usually affected?
Who is usually affected?
  • • Primarily Adults 
  • • There is a higher prevalence in men
  • • Most cases occur between 15 and 30 years old
  • • There are links to the mutations in the TP53 gene.


Common Bones Involved
Common Bones Involved
  • • Femur (upper leg)
  • • Humerus (upper arm)
  • • Ulna & Radius (forearm)
  • • Tibia & Fibula (lower leg)
  • • Phalanx (bone of a finger or toe)
Signs and Symptoms
Signs and Symptoms
  • • Local swelling and bone or joint pain.
  • • Pain may worsen with activity.
  • • A potential noticeable lump or mass.


Biological Behavior
Biological Behavior
  • • Periosteal Osteosarcomas malignant (cancerous) tumors that destroy bone
  • • They are typically slow-growing
  • • There is a moderate risk of recurrence after removal (resection) of the tumor
  • • The work-up often consists of physical examination, X-rays, CT scans, MRI, and sometimes bone scans are required.
  • • The diagnosis is often confirmed with a biopsy, which means taking a sample of tumor and having it analyzed

Risk to your limbs

Periosteal Osteosarcomas are cancerous aggressive tumors that, if left unchecked, will grow and destroy your normal bone. Clinically, local pain and swelling may be the first signs. As the tumor slowly grows, the bone is weakened and you are at an increased risk of breaking the bone due to the tumor (called a pathological fracture).

Radiographic imaging is used to help form a diagnosis. These include X-Ray, MRI, CT and Bone Scans

An example of an X-Ray is shown.

Periosteal Osteosarcoma

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Hey! I am Dr. Wittig.

Myself and my amazing team are dedicated to saving your life and your limb. Losing a limb because of a tumor can be a terrifying experience. But, it does not have to be the only option. I’ve spent 20+ years as a Board-Certified Orthopedic Surgeon and Orthopedic Oncologist.

I’ve devoted my career to helping children and adults afflicted with bone and soft tissue masses by performing complex limb saving surgeries. Most patients can have their limb saved, which may require innovative techniques.

Patients afflicted with musculoskeletal tumors have complex conditions that are best taken care of at large hospitals. I am the Chairman of Orthopedics and Chief of Orthopedic Oncology at Morristown Medical Center. My philosophy is a multidisciplinary team approach, working together to tailor treatment to individual patients. Education and research are essential to my practice, providing the best setting for extraordinary patient care. Because of this, we have some of the top results in the country.